The volume of a cylinder: \(\pi r^2 \cdot h\). h = height
The radius is 6 cm, and the height is 4*12 = 48 cm. The volume of the cylinder is \(36\pi \cdot 48 = 1728\pi\).
The volume of a sphere: \(\dfrac{4}{3} \pi r^3\).
The radius is 6 cm, and \(6^3 \) is 216. \(\dfrac{4}{3} \cdot 216 = 288\). The volume of one sphere is \(288\pi\). If we multiply by 4, the volume of the four spheres is \(1152\pi\).
We can calculate the empty cylinder space by subtracting 4 VolumeSphere from VolumeCylinder. We have \(1728\pi - 1152\pi\), which simplifies into \(\boxed{576\pi}\).