D**n, multiplication seemed logical to me, nevertheless this should be able to be figured out as well.
The last number is relatively easy since it's the result of $${{\mathtt{2}}}^{{\mathtt{n}}}$$, which means the last digit regularly skips between this array of numbers: 2,4,8,6.
For $${{\mathtt{2}}}^{\left({\mathtt{4}}{n}\right)}$$ the last digit is 6.
For $${{\mathtt{2}}}^{\left({\mathtt{4}}{n}{\mathtt{\,\small\textbf+\,}}{\mathtt{1}}\right)}$$ the last digit is 2.
For $${{\mathtt{2}}}^{\left({\mathtt{4}}{n}{\mathtt{\,\small\textbf+\,}}{\mathtt{2}}\right)}$$ the last digit is 4.
For $${{\mathtt{2}}}^{\left({\mathtt{4}}{n}{\mathtt{\,\small\textbf+\,}}{\mathtt{3}}\right)}$$ the last digit is 8.
We know the last digit is multiplied 1122 times, $${\frac{{\mathtt{1\,122}}}{{\mathtt{4}}}} = {\frac{{\mathtt{561}}}{{\mathtt{2}}}} = {\mathtt{280.5}}$$ so it is of the form $${{\mathtt{2}}}^{\left({\mathtt{4}}{n}{\mathtt{\,\small\textbf+\,}}{\mathtt{2}}\right)}$$ which means the last digit is 4.
While doing this I figured out a better way to solve this problem, we know this of the exponent:
$${\mathtt{1\,122}} = {\mathtt{2}}{\mathtt{\,\times\,}}{\mathtt{3}}{\mathtt{\,\times\,}}{\mathtt{11}}{\mathtt{\,\times\,}}{\mathtt{17}}$$
Another thing we know for sure is that while multiplying two numbers only the last two digits of each number affect the last two digits of the answer. Hence all digits save for the last two are irrelevant for further multiplication.
Since only the last two digits matter of the 1122 being multiplied we can drop the first two digits:
$${{\mathtt{22}}}^{{\mathtt{1\,122}}} = \left({\left({\left({\left({{\mathtt{22}}}^{{\mathtt{2}}}\right)}^{{\mathtt{3}}}\right)}^{{\mathtt{11}}}\right)}^{{\mathtt{17}}}\right)$$
$${\left({\left({{\mathtt{484}}}^{{\mathtt{3}}}\right)}^{{\mathtt{11}}}\right)}^{{\mathtt{17}}}$$
Only last two digits matter
$${\left({\left({{\mathtt{84}}}^{{\mathtt{3}}}\right)}^{{\mathtt{11}}}\right)}^{{\mathtt{17}}}$$
$${\left({{\mathtt{592\,704}}}^{{\mathtt{11}}}\right)}^{{\mathtt{17}}}$$
Only last two digits matter
$${\left({{\mathtt{4}}}^{{\mathtt{11}}}\right)}^{{\mathtt{17}}}$$
$${\left({{\mathtt{4}}}^{{\mathtt{11}}}\right)}^{{\mathtt{17}}} = {\left({\mathtt{4\,194\,304}}\right)}^{{\mathtt{17}}}$$
Only last two digits matter
$${{\mathtt{4}}}^{{\mathtt{17}}}$$
$${{\mathtt{4}}}^{{\mathtt{17}}} = {{\mathtt{4}}}^{{\mathtt{11}}}{\mathtt{\,\times\,}}{{\mathtt{4}}}^{{\mathtt{6}}} = {\mathtt{4\,194\,304}}{\mathtt{\,\times\,}}{{\mathtt{4}}}^{{\mathtt{6}}}$$
Only last two digits matter
$${\mathtt{4}}{\mathtt{\,\times\,}}{{\mathtt{4}}}^{{\mathtt{6}}} = {{\mathtt{4}}}^{{\mathtt{7}}} = {\mathtt{16\,384}}$$
Last two digits of $${{\mathtt{1\,122}}}^{{\mathtt{1\,122}}}$$ are 84, case closed.