The expression is ambiguous, but I'll assume you mean:
$$\frac{3/4(-8)}{2-3}$$
The order of operations are:
1. Solve what's in the paranthesis
2. Multiply (*) and divide (:)
3. Add (+) ans subtract (-)
We get:
$$\frac{3/4(-8)}{2-3} = \frac{3/-32}{-1}$$
Multiply both the numerator (top) and denominator (bottom) with -1
$$\frac{3/32}{1}=3/32 = 0.09375$$
.