To find the constant term in the expansion of $(2z - \frac{1}{z\sqrt{z}})^5$, we need to find the term that does not contain any powers of $z$.
The constant term can be obtained by selecting terms that contribute a power of $z^0$, which means we need to select one term from each of the two factors in the expansion. We can choose the $2z$ term or the $-\frac{1}{z\sqrt{z}}$ term from each factor.
For the $2z$ term, we need to choose it 0 times, 1 time, 2 times, 3 times, 4 times, or 5 times. Similarly, for the $-\frac{1}{z\sqrt{z}}$ term, we need to choose it 0 times, 1 time, 2 times, 3 times, 4 times, or 5 times.
We want to choose terms that result in a power of $z^0$, so we need to choose the $-\frac{1}{z\sqrt{z}}$ term 5 times, and the $2z$ term 0 times. Therefore, the constant term in the expansion is 60.