(5 × 10-12)(5 × 1016)
$$\left({\mathtt{5}}{\mathtt{\,\times\,}}{\mathtt{10}}{\mathtt{\,-\,}}{\mathtt{12}}\right){\mathtt{\,\times\,}}\left({\mathtt{5}}{\mathtt{\,\times\,}}{\mathtt{1\,016}}\right) = {\mathtt{193\,040}}$$