What is the slope of the line containing the midpoint of the segment with endpoints at $(2, 4)$ and $(0, -2)$ and the midpoint of the segment with endpoints at $(5, 1)$ and $(1, 5)?$ Express your answer in simplest form.
Midpoint1 = 1,1
Midpoint2 = 3,3 slope = (y1-y2)/(x1-x2) = (1-3)/(1-3) = 1