I suppose that we're solving for x here.
2 - 3x/8 = 0
-3x/8 = -2
-3x = -16
x = 16/3
If the problem wasn't to solve for x, then I suppose you meant that you wanted this simplified, in which case I believe the following makes a simpler form:
2 - (3x)/8
16/8 - (3x)/8
(16-3x)/8