If the sequence is B, C, E, H
and if you replace the letter with its place in the alphabet,
then the sequence becomes: 2, 3, 5, 8.
This could be a Fibonacci sequence where, after the first two terms, the next term is found be adding the preceding two terms.
This results in the next term being 5 + 8 = 13, which corresponds to letter M.
The negative signs are bothersome, but do not invalidate the result ...
If the sequence is B, C, E, H
and if you replace the letter with its place in the alphabet,
then the sequence becomes: 2, 3, 5, 8.
This could be a Fibonacci sequence where, after the first two terms, the next term is found be adding the preceding two terms.
This results in the next term being 5 + 8 = 13, which corresponds to letter M.
The negative signs are bothersome, but do not invalidate the result ...